Sarcoids

Sarcoids

Sarcoids are the most common skin tumors in horses and can occur in various locations on the body. These benign tumors are usually slow-growing, but in some cases, they can become painful or affect the horse's quality of life. Sarcoids are not malignant, but their treatment and monitoring are important to avoid potential complications. 

Symptoms

Sarcoids can appear in different forms and vary in size, appearance, and location. The most common symptoms include:

  • Nodules or growths on the skin: 
    Sarcoids often appear as small, raised nodules or warts on the horse's skin. They can also be flat, hairless spots. These can change in size and shape. There are about 5 different forms.
  • Altered skin texture: 
    The tumors are often hardened and may have an irregular surface that can be rough or smooth.
  • Bleeding or discharge: 
    Sarcoids that occur on mucous membranes or in areas with high friction (e.g., eyelids or genital area) can bleed or become purulent.
     
  • Itching or skin irritations: 
    The affected area may experience itching, skin irritations, or pain, prompting the horse to scratch or rub more frequently.
  • Enlargement or spread: 
    Sarcoids can grow over time and spread to adjacent skin areas.
     

Causes

The exact cause of sarcoid development is not yet fully understood, but several factors are associated with their occurrence:

  • Viral infection: 
    Sarcoids are often linked to the bovine papillomavirus (BPV). This virus is widespread in horses and can cause skin tumors under certain conditions.
  • Genetic predisposition: 
    It is believed that some horse breeds have a genetic predisposition to develop sarcoids. Particularly, Thoroughbreds, Arabs, draft horses, and some warmbloods show a higher frequency.
       
     
  • Injuries or skin irritations: 
    Frequent skin injuries, scarring, or chronic skin irritations can promote the development of sarcoids, especially in areas that are repeatedly subjected to mechanical stress.
  • Immune system: 
    A weakened immune system can facilitate the development of sarcoids, as the immune system normally helps control abnormal cell growth processes.
     

Diagnose

The diagnosis of a sarcoid in a horse is made by the veterinarian using various methods to accurately determine the tumor and its characteristics. A thorough clinical examination is the first step, where the veterinarian carefully inspects the horse for growths or changes in skin texture. The size, shape, and location of the tumors are assessed to make an initial evaluation.

To ensure that it is indeed a sarcoid, a biopsy may be performed. The veterinarian takes a skin sample, which is then examined microscopically. This examination helps distinguish the sarcoid from other possible skin changes.

In cases of deep or hard-to-reach sarcoids, the veterinarian may use imaging techniques such as ultrasound. This procedure helps assess the extent of the tumor and any potential effects on deeper tissues.

Another important part of the diagnosis is the differential diagnosis. This checks whether it is not another skin disease or tumor that can cause similar symptoms. This precise clarification is important to make an accurate diagnosis and enable appropriate treatment.
 

Treatment

The treatment of sarcoids in horses is usually tailored to the individual and depends on the type, size, and location of the tumor. Due to the different responses of sarcoids to various treatment methods, each case requires a customized therapy. The most common treatment options include:

  • Surgical removal: One possible treatment for sarcoids is the surgical removal of the tumor. The tumor is completely excised to prevent recurrence. However, there is a possibility that the tumors may recur if not all affected cells are removed.
  • Cryotherapy (cold treatment): For smaller sarcoids, cryotherapy, where the tumors are frozen with liquid nitrogen, can be an effective method. This treatment destroys abnormal cells and allows the sarcoid to heal.
  • Laser treatment: The use of laser light is particularly suitable for hard-to-reach sarcoids. The laser can reduce or remove tumors.
  • Chemotherapy: A medical treatment, such as Imiquimod or 5-Fluorouracil, can be used to combat sarcoids. These medications promote the horse's immune response and inhibit tumor cell growth. Other chemotherapeutic ointments also offer an effective option for local sarcoid treatment.
  • Radiation therapy: In some cases, when other methods are not sufficiently effective, radiation therapy can be used to treat sarcoids. It helps shrink the tumors or stop their growth.
  • Immunomodulators: Some treatments, such as the use of Bacillus Calmette-Guerin (BCG) vaccines, aim to stimulate the immune system to fight the tumor.

The choice of the right treatment depends on the individual case, which is why close collaboration with the veterinarian is necessary to choose the best therapy option.